Collagen is the main protein in connective tissue. It helps to maintain the firmness, tone and turgidity of the skin, making it a valuable ally against skin ageing. Collagen is therefore one of the main factors that help to maintain a healthy skin. With advancing age, the synthesis of new collagen decreases, and its degradation increases. The supply of type I Collagen in the dermis stimulates the cells used for its production, called fibroblasts, to reproduce generating neo-collagen. Because the contribution of collagen from the outside is effective it is important that this maintains perfectly the characteristics of the native one even after its extraction. The production technology must absolutely respect its biological structure, strictly maintaining its purity with the absence of chemical residues.

Collagen is a fibrous protein that makes up the ECM of human tissues, including: skin, tendons, ligaments, cartilage, bones and teeth. It represents about 25% of the total protein in the human body. By driving the process of tissue repair, collagen plays an important role in the biological process of healing. Its mechanical action provides structural support, which helps to:

• Create a supporting structure (scaffolding) for the recovery of lost substances
• Control the differentiation, migration and synthesis of many cellular proteins
• Enhance the physiological formation of fibroblasts, granulation tissue and native collagen
• Facilitate the contact of platelets and coagulation factors (haemostasis)
• Aid the formation of new capillaries (angiogenesis)

• With its triple helix structure, heterologous native type I collagen gives rise to effects that can be superimposed on those of tissue collagen.
• Of the various collagens derived from animals, the equine type does not carry the risks associated with bovine spongiform encephalopathy (BSE). It is can be seen as the “gold standard”
• It is extracted from horse tendon and purified through high-tech processes that do not change its properties, making it compatible with autologous tissue collagen.